试议免疫性小儿免疫性血小板减少症30例临床分析工作
最后更新时间:2024-02-20
作者:用户投稿本站原创
点赞:6999
浏览:20514
论文导读:achnormalbutstoppedbleeding,onepatientprogressedintoEvanssyndrome,onepatienttranerredintochronicdisease.ConclusionITPischaracterizedbythrombocytopenia,itanifestionisspontaneoushemorrhageofskin,mucouembrane,defectivebloodclotretraction,prolongedbleedingandsoon,
[摘要] 目的 探讨小儿免疫性血小板减少症(ITP)的临床特点及预后。 方法 对30例ITP患儿的临床资料进行分析,建立档案,分析患儿的出血症状、血常规、骨髓象、治疗依从情况及预后等。 结果 全部病例均有皮肤出血,鼻出血5例(17%),消化道出血3例(10%),颅内出血1例(3%),死亡1例,合并布加综合征(腹水、黄疸、肝功能损伤)1例(3%),15例随访1年余已完全康复,10例血小板未恢复正常但已无出血症状,转为Evans综合征1例,转为慢性1例。 结论 ITP以持续的血小板计数减少为特征,临床表现为皮肤、黏膜自发性出血,血块收缩不良,出血时间延长等,且影响其预后的因素是多方面的。
[关键词] 免疫性;血小板减少;血常规;骨髓检查;激素及免疫球蛋白治疗;预后
[] B [文章编号] 1674-4721(2013)11(b)-0172-02
Clinical analysis of 30 cases of pediatric immune thrombocytopenia
LU Rui
The First Department of Pediatrics,Wenshan Zhou Hospital in Yunnan Province,Wenshan 663000,China
[Abstract] Objective To investigate the clinical characteristics and prognosis of pediatric immune thrombocytopenia (ITP). Methods Clinical data of 30 children with ITP was analyzed and filed.The children′s bleeding symptom,blood routine,myelogram,treatment compliance and prognosis were analyzed. Results All the patients had dermatorrhagia,among them, 5 (17%) patients had nose bleeding,3 (10%) patients had gastrointestinal bleeding and 1 (3%) patient had intracranial bleeding,one patient died and 1 (3%) patient was complicated by Budd-Chiari syndrome (ascites,jaundice,liver damage).15 patients fully recovered after more than 1 year′s follow-up,and platelet status in 10 patients did not reach normal but stopped bleeding,one patient progressed into Evans syndrome,one patient tranerred into chronic disease. Conclusion ITP is characterized by thrombocytopenia,its manifestion is spontaneous hemorrhage of skin,mucous membrane,defective blood clot retraction,prolonged bleeding and so on,and the factors influencing the prognosis is in many aspects.
[Key words] Immunity;Thrombocytopenia;Blood routine;Bone marrow examination;Hormones and immunoglobulin treatment;Prognosis
免疫性血小板减少症(immune thrombocytopeni论文导读:
a,ITP)是小儿最常见的免疫性疾病,其特点是自发性出血,它的症状和体征在个体间差别较大,很多患儿无症状或只有轻微皮肤出血,有的则有严重出血,如消化道出血、广泛的皮肤黏膜出血、颅内出血。血小板减少即可能发生出血,但其减少的程度与是否发生出血不完全相关。本研究就本院收治的ITP患儿的症状、实验室检查、治疗及预后等进行总结分析,现报告如下。
1 资料与方法
[摘要] 目的 探讨小儿免疫性血小板减少症(ITP)的临床特点及预后。 方法 对30例ITP患儿的临床资料进行分析,建立档案,分析患儿的出血症状、血常规、骨髓象、治疗依从情况及预后等。 结果 全部病例均有皮肤出血,鼻出血5例(17%),消化道出血3例(10%),颅内出血1例(3%),死亡1例,合并布加综合征(腹水、黄疸、肝功能损伤)1例(3%),15例随访1年余已完全康复,10例血小板未恢复正常但已无出血症状,转为Evans综合征1例,转为慢性1例。 结论 ITP以持续的血小板计数减少为特征,临床表现为皮肤、黏膜自发性出血,血块收缩不良,出血时间延长等,且影响其预后的因素是多方面的。
[关键词] 免疫性;血小板减少;血常规;骨髓检查;激素及免疫球蛋白治疗;预后
[] B [文章编号] 1674-4721(2013)11(b)-0172-02
Clinical analysis of 30 cases of pediatric immune thrombocytopenia
LU Rui
The First Department of Pediatrics,Wenshan Zhou Hospital in Yunnan Province,Wenshan 663000,China
[Abstract] Objective To investigate the clinical characteristics and prognosis of pediatric immune thrombocytopenia (ITP). Methods Clinical data of 30 children with ITP was analyzed and filed.The children′s bleeding symptom,blood routine,myelogram,treatment compliance and prognosis were analyzed. Results All the patients had dermatorrhagia,among them, 5 (17%) patients had nose bleeding,3 (10%) patients had gastrointestinal bleeding and 1 (3%) patient had intracranial bleeding,one patient died and 1 (3%) patient was complicated by Budd-Chiari syndrome (ascites,jaundice,liver damage).15 patients fully recovered after more than 1 year′s follow-up,and platelet status in 10 patients did not reach normal but stopped bleeding,one patient progressed into Evans syndrome,one patient tranerred into chronic disease. Conclusion ITP is characterized by thrombocytopenia,its manifestion is spontaneous hemorrhage of skin,mucous membrane,defective blood clot retraction,prolonged bleeding and so on,and the factors influencing the prognosis is in many aspects.
[Key words] Immunity;Thrombocytopenia;Blood routine;Bone marrow examination;Hormones and immunoglobulin treatment;Prognosis
免疫性血小板减少症(immune thrombocytopeni论文导读:
a,ITP)是小儿最常见的免疫性疾病,其特点是自发性出血,它的症状和体征在个体间差别较大,很多患儿无症状或只有轻微皮肤出血,有的则有严重出血,如消化道出血、广泛的皮肤黏膜出血、颅内出血。血小板减少即可能发生出血,但其减少的程度与是否发生出血不完全相关。本研究就本院收治的ITP患儿的症状、实验室检查、治疗及预后等进行总结分析,现报告如下。
1 资料与方法