免费论文查重: 大雅 万方 维普 turnitin paperpass

浅析消化道奥美拉唑治疗急性非静脉曲张性上消化道出血效果观察学术

最后更新时间:2024-01-26 作者:用户投稿原创标记本站原创 点赞:6565 浏览:14176
论文导读:,在常规治疗的基础上给予奥美拉唑治疗,观察治疗效果,报道如下。1资料与方法

1.1一般资12下一页

[摘要] 目的 探讨奥美拉唑治疗急性非静脉曲张性上消化道出血的疗效性和安全性。 方法 选择2010年1月~2012年12月本院收治的98例急性非静脉曲张性上消化道出血患者作为观察对象,根据不同用药方法分为观察组(47例)和对照组(51例),对照组给予常规治疗,观察组在对照组基础上给予奥美拉唑静脉滴注,观察两组的疗效性和安全性。 结果 观察组总有效率达95.7%,对照组总有效率为72.5%,两组差异有统计学意义(P<0.05);观察组止血时间较对照组明显缩短,差异具有统计学意义(P<0.05);两组在治疗过程中未见明显不良反应。结论 奥美拉唑结合常规方法治疗急性非静脉曲张性上消化道出血临床疗效显著,止血时间较短,安全性较高,值得临床推广应用。
[关键词] 非静脉曲张性上消化道出血;奥美拉唑;止血敏;疗效观察
[] A [文章编号] 1674-4721(2013)11(b)-0080-02
Observation on the effect of omeprazole in the treatment of acute non variceal upper gastrointestinal hemorrhage
LAI Shen-wei ZHANG Xu ZHU SHU-sheng
Department of Internal Medicine of Digestive Tumor, People′s Hospital of Yudu County in Jiangxi Province, Yudu 342300,China
[Abstract] Objective To investigate the efficacy and safety of omeprazole in the treatment of patients with acute non variceal upper digestive tract hemorrhage. Methods 98 cases of patients with acute non variceal upper gastrointestinal bleeding from January 2010 to December 2012 in our hospital were selected as research objects, according to the different drugs, the cases were divided into observation group (47 cases) and control group(51 cases), control group was given conventional treatment, observation group was given omeprazole note based on control group, the effect and safety of the two groups were observed. Results In observation group, the total effective rate was 95.7%, that of control group was 72.5%,the difference between two groups was significant (P<0.05);bleeding stop time of observation group was significantly shorter than control group, the difference was statistically significant(P<0.05); no obvious adverse reaction in two groups was found in the course of treatment. Conclusion The effect of omeprazole in the treatment of acute non variceal upper gastrointestinal hemorrhage is exact, hemostatic time is short, security is high, is worthy of clinical application.
[Key words] Non variceal upper gastrointestinal bleeding; Omeprazole; Dicynone; Curative effect observation
急性上消化道出血是临床常见危急重症,出血部位包括食管、胃、十二指肠、胰腺等,症状以呕血或黑便为主。如不能及时止血,则有可能导致失血性休克等并发症,随时危及患者生命。急性上消化道出血分为静脉曲张性上消化道出血和非静脉曲张性上消化道出血,病情均较危急,临床治疗本疾病的关键在于通过药物、内镜及外科手术等多种方法进行止血。随着上消化道出血诊断和治疗水平的快速提高,内镜下对出血部位进行止血药物注射能够较大程度地降低患者手术率,但存在较大风险。药物治疗在临床上趋于多样化,因此选择良好的治疗方案尤其重要。本研究选择近3年本院98例非静脉曲张性上消化道出血患者,在常规治疗的基础上给予奥美拉唑治疗,观察治疗效果,报道如下。
1 资料与方法

1.1 一般资论文导读:源于:论文模板www.7ctime.com上一页12


选择2010年1月~2012年12月本院收治的急性非静脉曲张性上消化道出血患者作为观察对象,共纳入患者98例。诊断及纳入标准[3]:①年龄18~70周岁;②符合《中华内科杂志》制定的急性非静脉曲张性上消化道出血诊治指南(2005草案),且出血量不超过1000 ml(上消化道出血中级以下患者);③患者均存在便血症状。排除一般状况较差,有严重心、肝、肾功能不全的患者。根据不同用药方法分为观察组和对照组。观察组47例,其中,男23例,摘自:硕士论文答辩技巧www.7ctime.com
女24例,平均年龄(51.3±2.3)岁,平均病程(2.1±1.3)年,出血量<500 ml患者14例,出血量500~1000 ml患者33例,其中消化性溃疡占30%以上,其他患者为急性胃黏膜病变等;对照组51例,其中,男29例,女22例,平均年龄(52.7±1.9)岁,平均(2.0±1.9)年,出血量0.05),具有可比性。 源于:论文模板www.7ctime.com