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试论晕厥98例小儿晕厥临床分析结论

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[摘要] 目的 探讨小儿晕厥的病因及美托洛尔治疗小儿血管迷走性晕厥(VVS)的疗效,为临床诊治提供依据。 方法 采用卧位立位血压、血常规、血糖浓度、血气分析、心电图、超声心动图、头颅CT、脑电图、24 h动态心电图以及直立倾斜试验(HUT)等检测指标,以鉴别得病的原因;将VVS患儿随机平均分为治疗组(口服美托洛尔片)及对照组(口服复合维生素B片),观察两组患者临床晕厥发作次数及HUT结果。 结果 小儿自主神经介导晕厥发病率最高(64.3%),其中VVS晕厥发病最多(66.7%)。治疗组经美托洛尔治疗后有效率为85.7%,HUT阴转率为66.7%;对照组有效率为42.8%,HUT阴转率为44.4%;两组有效率差异有统计学意义(P<0.05)。 结论 小儿自主神经介导晕厥发病率最高,尤其以VVS晕厥最多见;口服美托洛尔片可有效治疗小儿VVS晕厥。
[关键词] 小儿晕厥;血管迷走神经性晕厥;美托洛尔
[] A [文章编号] 1674-4721(2013)11(b)-0045源于:毕业设计论文总结www.7ctime.com
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Clinical analysis of 98 cases of paediatric syncope
WANG Yi-chang
Department of Pediatrics,Mianhu Overseas Chinese Hospital of Jiexi County,Jieyang City in Guangdong Province,Jiexi 515438,China
[Abstract] Objective To study the etiology of paediatric syncope and the curative effect of metoprolol on pediatric vasovagal syncope (VVS) to provide the basis for clinical diagnosis and treatment.Methods The blood pressure in lying position,blood routine test,blood sugar concentration,blood gas analysis,electrocardiogram,echocardiography,cranial computed tomography (CT),electroencephalogram,24 h dynamic electrocardiogram,and head-up tilt test (HUT) were used to identify the cause of the disease;Children with VVS were randomly divided into treatment group (metoprolol tablets orally) and control group (Vitamin B tablets orally),the clinical onset of syncope and HUT outcome of the two groups was observed.Results The incidence of paediatric autonomic nerve mediated syncope was the highest (64.3%),in which the highest was VVS syncope pathogenesis (66.7%).The effective rate of the treatment group after treatment with metoprolol was 85.7% and the negative conversion rate of HUT was 66.7%;the effective rate of the control group was 42.8% and the negative conversion rate of HUT was 44.4%,there was significant difference of the result between the t论文导读:
wo groups (P<0.05).Conclusion The incidence of paediatric autonomic nerve mediated syncope is the highest,especially VVS syncope;Oral administration of metoprolol tablets can effectively treat paediatric VVS syncope.
[Key words] Paediatric syncope;Vasovagal syncope;Metoprolol
晕厥是一种由于大脑供血不足导致的短暂性意识丧失,经常伴有肌张力丧失或降低,进而失去维持自主体位的能力,在儿童中经常发生。据统计,欧洲国家2000~2009年每10万儿童中有125人发生晕厥,且发病率呈上升趋势。本研究探讨小儿晕厥的病因及美托洛尔治疗小儿血管迷走性晕厥(VVS)的疗效,为临床诊治提供依据。
1 资料与方法

1.1 临床资料

选择本院儿科2009年1月~2012年6月接受治疗的98例小儿晕厥患者为实验对象,其中,男57例,女41例;年龄5~16岁,平均9.65岁。同期确诊为VVS的患儿共42例,随机均分为治疗组与对照组。治疗组21例患儿,男9例,女12例,年龄6~14岁,平均9.15岁;对照组21例,男11例,女10例,年龄5~15岁,平均9.50岁。两组患儿均达到儿童晕厥诊断指南标准,性别、年龄等一般资料差异无统计学意义(P>0.05)。 源于:电大毕业论文www.7ctime.com